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Autoimmune lymphoproliferative syndrome

3 OMIM references -
5 associated genes
No signs/symptoms info

PROTEIN INTERACTIONS: 1

Bladder exstrophy

1 OMIM reference -
1 associated gene
14 signs/symptoms

Autoimmune lymphoproliferative syndrome

Bladder exstrophy

CASP10	(UniProt - OMIM)		TP63	(UniProt - OMIM)
FAS	(UniProt - OMIM)
FASLG	(UniProt - OMIM)
NRAS	(UniProt - OMIM)
PRKCD	(UniProt - OMIM)


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	FAS	(0.63)	TP63

Citations in the biomedical literature:

Autoimmune lymphoproliferative syndrome		Bladder exstrophy
	Synonym(s): - ALPS - Canale-Smith syndrome - FAS deficiency		Synonym(s): - Classic exstrophy of the bladder

	Classification (Orphanet): - Rare genetic disease - Rare hematologic disease - Rare immune disease - Rare oncologic disease		Classification (Orphanet): - Rare abdominal surgical disease - Rare developmental defect during embryogenesis - Rare genetic disease - Rare renal disease - Rare urogenital disease

	Classification (ICD10): - Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism -		Classification (ICD10): - Congenital malformations, deformations and chromosomal abnormalities -

	Epidemiological data: Class of prevalence: unknown Average age onset: variable Average age of death: - Type of inheritance: autosomal dominant		Epidemiological data: Class of prevalence: 1-9 / 100 000 Average age onset: neonatal/infancy Average age of death: normal Type of inheritance: multigenic/multifactorial

	External references: 3 OMIM references - 1 MeSH reference: D056735		External references: 1 OMIM reference - 1 MeSH reference: D001746

Bladder exstrophy
	Very frequent - Anus / rectum anomalies - Bladder / cloacal exstrophy - Clitoris / labia majora / labia minora / female external genitalia hypoplasia - Hypospadias / epispadias / bent penis - Micropenis / small penis / agenesis - Umbilical hernia - Vesicorenal / vesicoureteral reflux Frequent - Inguinal / inguinoscrotal / crural hernia - Recurrent urinary infections - Urethral anomalies / stenosis / posterior urethral valves / megalocystis Occasional - Encopresis / fecal incontinence - Intestinal / gut / bowel malrotation - Omphalocele / exomphalos - Short bowel
Autoimmune lymphoproliferative syndrome
(no data available)